Thryv Therapeutics Inc., a biotechnology company pioneering treatments for genetic and cardiometabolic conditions, including congenital Long QT Syndrome, heart failure, and atrial fibrillation, has completed phase 1 dosing of its second SGK1 inhibitor. 

Thryv Therapeutics Inc., a clinical-stage biotechnology company pioneering novel therapies for cardiovascular diseases, is pleased to announce its participation in four prominent healthcare investor conferences over the coming weeks, providing critical updates on its advancements in precision medicine. 

Thryv Therapeutics Inc., a clinical-stage biotechnology company, is proud to announce its sponsorship and active participation in the 2024 International Sudden Arrhythmia Death Syndromes (SADS) Foundation Family Conference, taking place in Chicago, Illinois from November 8^th to 9^th, 2024.

Thryv Therapeutics Inc., a biotechnology company pioneering precision treatments for cardiovascular conditions, including congenital Long QT Syndrome, atrial fibrillation and heart failure, is proud to announce the acceptance of four abstracts for presentation at the prestigious American Heart Association’s (AHA) 2024 Annual Scientific Sessions. 

Thryv Therapeutics Inc., a clinical-stage biotechnology company, received positive top-line results from the Wave I Part 2 proof-of-concept clinical study evaluating LQT-1213 for the treatment of congenital Long QT Syndrome (cLQTS) Types 2 and 3.

Thryv Therapeutics Inc. today announced that the United States Food and Drug Administration (FDA) has granted Orphan Drug Designation to LQT-1213 for the treatment of Long QT Syndrome (LQTS).  LQT-1213 is a novel, first-in-class SGK1 inhibitor specifically designed to treat congenital LQTS.

Thryv Therapeutics announced today its participation in the upcoming 2024 RBC Capital Markets Private Company Virtual Conference. Thryv will attend on Tuesday, October 1st, 2024, and will sit for a fireside chat from 10:30 a.m. to 11:00 a.m. ET.

To schedule one-on-one meetings with the team, please contact admin@thryvtrx.com. 

Thryv Therapeutics is pleased to announce that it will be hosting investor meetings at the Jefferies Global Healthcare Conference on Tuesday, June 4, 2024, at the Hyatt Grand Central New York.

This year’s gathering will bring together 3,000 leading executives to address near-and long-term investment opportunities as well as current trends driving healthcare in the U.S. and internationally.

To schedule a meeting with Thryv Therapeutics throughout the day, please contact admin@thryvtrx.com.

Thryv Therapeutics Inc., a biotechnology company pioneering precision treatment to treat indications including Congenital Long QT Syndrome, atrial fibrillation, and heart failure, today announced a poster presentation of SGK1 inhibition in models of Drug-Induced QT prolongation at the 2024 Heart Rhythm Society meeting in Boston, MA. This presentation will take place on Friday, May 17th, from 10:30 a.m. to 12:30 p.m. ET. The meeting will commence with a presentation by Thryv co-founder and Principal Scientific Advisor, Dr. Saumya Das, at the Stanford Biodesign New Arrhythmia Technologies Retreat in Boston, where he will discuss Small Molecules for Arrhythmia Therapy.

Thryv Therapeutics is pleased to announce that it will be hosting investor meetings at the Piper Sandler Spring Biopharma Symposium on Tuesday, April 16, 2024, at the Encore Boston Harbor.

Thryv Therapeutics is pleased to announce its selection as a featured presenter at the 2024 Bloom Burton & Co. Healthcare Investor Conference. The virtual presentation will take place on Tuesday, April 16th, 2024, from 3:00 p.m. to 3:30 p.m. ET.

Thryv Therapeutics is pleased to announce the presentation of its poster: SGK1 inhibitor LQT-1213 significantly attenuates dofetilide-induced QT prolongation in humans: Results of the WAVE I Clinical Study at the American College of Cardiology Conference. Thryv’s poster presentation will be presented on Sunday, April 7th from 12:15 p.m. - 1:00 p.m. in Hall B4-5.

Thryv Therapeutics is pleased to announce its selection as a featured presenter at the Evercore ISI 2024 Emerging Biotech Conference that is taking place virtually on February 28th and 29th, 2024. Thryv’s virtual presentation will be on February 28th from 2:15-2:45 p.m. ET.

Reflecting on an incredible year! Our 2023 Year End Report highlights Thryv's milestones in Long QT Syndrome, atrial fibrillation, heart failure, and oncology. From clinical studies to publications and presentations, it's been an exciting year! Huge thanks to our dedicated team, collaborators, and the Thryv community for making it all possible. Here's to an even brighter 2024!

Thryv Therapeutics is pleased to announce its selection as a featured presenter at the 2023 RBC Capital Markets Private Company Conference. The virtual presentation will take place on Thursday, December 14th, 2023, from 10:40 a.m. to 11:10 a.m. ET.

Thryv Therapeutics is pleased to announce its selection as a featured presenter at the Piper Sandler 35th Annual Healthcare Conference, held from November 28th to November 30th, 2023, at Lotte New York Palace in New York City. Paul Truex, Thryv’s Chairman of the Board & Chief Executive Officer, will present on November 29th from 3:50 to 4:10 PM in Harlem Track | Kennedy 2, 4th floor.

Thryv Therapeutics Inc. is pleased to announce an oral presentation of the effects of SGK-1 inhibition with its’ potent and selective inhibitor THRV-1268 on atrial fibrillation in an obese-mouse model. This abstract will be presented during the Shocking Results: Basic Science Insights into Arrhythmias session at the American Heart Association Annual Scientific Sessions in Philadelphia, PA.

Thryv Therapeutics Inc. today announced positive results of the WAVE 1 Proof of Concept clinical study evaluating LQT-1213 for the reduction of QTcF in individuals with dofetilide-induced long QT. LQT-1213 is a potent and selective inhibitor of Serum Glucocorticoid inducible Kinase 1 (SGK-1), which is implicated in QTc prolongation.

“We are excited to advance our portfolio of potent SGK1 inhibitors into the treatment of aggressive, treatment resistant cancers. SGK1 has been implicated in a number of treatment-resistance oncology pathways and our work has demonstrated the potential to delay resistance and restore activity of approved therapies and ultimately improve progression free and overall survival outcomes,” said Debra Odink, President, and Chief Development Officer.

While we await results from our initial proof of efficacy study this summer in Long QT Syndrome, we are able to accelerate a number of pipeline initiatives thanks to this new investment from IQ.